Angelica Panganiban was born in Payatas on November 4, 1986. Her mother is a Filipina who died in 2008 and buried in Singapore while her father is an American from Iowa, United States. She uses the surname Panganiban from her adopted family.
Panganiban finished elementary school in 1999 at St. Vincent in Teacher’s Village, Quezon City, and high school in 2003 at St. Vincent, West Avenue. She was the Junior-Senior Prom Princess in 2002 and Miss Junior and Senior Prom in 2003. She was a cheerleader and also a feature editor in her school newspaper. She attended college at Thames International Business School, majoring in Mass Communication.